Mark Slifka, Ph.D.

Oregon National Primate Research Center senior scientist; OHSU School of Medicine professor of microbiology and immunology

Oregon National Primate Research Center senior scientist; OHSU School of Medicine professor of microbiology and immunology

Area(s) of expertise:
  • Vaccine development
  • Education and clinical research
  • Dengue virus
  • Zika virus
  • West Nile virus
  • Yellow fever
  • Chikungunya virus
  • Nonhuman primate model research
  • Tetanus
  • Diphtheria
  • Smallpox
  • Immunological memory

Dr. Slifka investigates the underlying mechanisms of humoral and cell-mediated immunity against acute and chronic viral infections.This work has included developing several models of viral infection and/or vaccination in order to address basic immunological questions related to the development and maintenance of long-term protective immunity.

Slifka and colleagues also have developed a series of clinical studies in which they study immunological memory directly in human subjects. During the course of this work, they study a number of viruses including arenaviruses (lymphocytic choriomeningitis virus, LCMV), alphaviruses (chikungunya virus, Eastern-, Western-, and Venezualen equine encephalitis viruses), flaviviruses (West Nile virus, yellow fever, dengue and Zika), and orthopoxviruses (vaccinia, cowpox, and monkeypox). 

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