Parkinson's research
Credit: OHSU News
A mouse model of Parkinson's disease and dementia with Lewy bodies shows abnormal aggregated alpha-synuclein Lewy pathology within neurons in the brain’s hippocampus. New research suggests that alpha-nuclein proteins repair DNA breaks within the nucleus of brain cells. When they cluster outside the nucleus, as shown here, it can lead to cellular dysfunction and death. (OHSU)