Blood vessel on-a-chip identifies how perivascular cells can worsen chronic disease
January 13, 2025
New research led by Luiz Bertassoni, Ph.D., uncovers how specialized cells surrounding small blood vessels contribute to blood vessel dysfunction in chronic diseases such as cancer, diabetes and fibrosis. He says, “Our findings represent a paradigm shift, showing how perivascular cells, instead, act as important sentinels. They detect changes in tissues and coordinating vascular responses. This opens the door to entirely new treatment strategies.”