OHSU in the news

Gene therapy improves vision in Leber congenital amaurosis patients

Optometry Today May 10, 2024
An OHSU study finds about 79% of clinical trial participants with leber congenital amaurosis experienced measurable improvement after receiving experimental, CRISPR-based gene editing: “This [is] a blinding disease with no treatments ... an enormous burden on patients [due] to their vision loss,” says Mark Pennesi, M.D., Ph.D.

Calls to poison centers for fentanyl exposure in kids increased nearly 54-fold since 2016

ABC News May 10, 2024
Calls to poison centers, including the Oregon Poison Center at OHSU, for illicit fentanyl exposures in kids younger than 6 increased from 10 cases in 2016 to 539 in 2023. Rob Hendrickson, M.D., says: "It is imperative that the community provides resources to end the fentanyl epidemic and that people who use illicit drugs secure them from children by using opaque child-resistant lockable containers. We are extremely concerned about what we are seeing in the community and will continue to bring the issue to the forefront to raise awareness about how to prevent unintentional exposures among children."

There’s a New Covid Variant. What Will That Mean for Spring and Summer?

The New York Times May 10, 2024
In a The New York Times article about a new variant called KP.2, Fikadu Taffese, Ph.D., says researchers are still trying to determine to what degree repeat infections raise the risk of developing long COVID, as the pandemic continues to evolve. “That’s the nature of the virus. It keeps mutating," Tafesse says.

Urology Clinic announces improved imaging for prostate cancer patients

The Daily Astorian May 09, 2024
The Columbia Memorial Hospital-Oregon Health & Science University Health Urology Clinic now offers men with prostate cancer targeted positron emission tomography imaging with Pylarify, an imaging agent approved by the Food and Drug Administration to identify suspected metastasis or a return of prostate cancer.

Kummar on the Investigation of Rezatapopt in TP53 Y220C–Mutated Advanced Solid Tumors

OncLive May 09, 2024
In a podcast interview with OncLive On Air, Shivaani Kummar, M.D., discusses the ongoing investigation of the first-in-class p53 therapy rezatapopt for patients with mutated advanced solid tumors. Kummar says: “I’ve been doing drug development for over 20 years, and I find that this point is one of the most exciting times in this field as we now have the ability to specifically design molecules against molecular targets within cancer cells as well as a slew of different types of agents that target the tumor microenvironment and the immune cells.”

CRISPR-based gene editing treatment shows promise for rare eye disorder

Medical News Today May 09, 2024
An OHSU study finds about 79% of clinical trial participants with leber congenital amaurosis experienced measurable improvement after receiving experimental, CRISPR-based gene editing: “This [is] a blinding disease with no treatments ... an enormous burden on patients [due] to their vision loss,” says Mark Pennesi, M.D., Ph.D.
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