The Oregon Clinical & Translational Research Institute at OHSU has received a $37 million boost from the federal government to help accelerate the translation of research into clinical use, medical practice and health policy.
Scientists in the Vollum Institute at OHSU have identified an enzyme that plays a crucial role in the degeneration of axons, the threadlike portions of a nerve cell that transmit signals within the nervous system.
Claudio Mello, Ph.D., a professor of behavioral neuroscience in the OHSU School of Medicine who studies zebra finches shares his thoughts about the role of birds in understanding human biology and his growing appreciation for the natural world.
A systematic review of basic and clinical science research has revealed no definitive standard for detecting military veterans at risk of suicidal behavior, nor is there a clear standard of treatment to prevent suicide among U.S. veterans.
Chris Ramsey, a physical therapist who lives in Beaverton, Oregon, is currently training for the Race Across the West, a 930-mile bike race from southern California to Colorado that begins June 13. Notably, he is believed to be the first person with MS to attempt the race solo.
Kevin Wright, Ph.D. is an assistant professor running his own laboratory in OHSU’s Vollum Institute, where he applies his natural curiosity toward solving one of the most formidable puzzles in science and medicine: how the nervous system works.
Elizabeth Whispell maintains an active lifestyle, so she didn’t give much thought to what seemed to be subtle changes in her appearance. It wasn’t until later that she learned she actually had a rare pituitary disorder – a condition serious enough that it ultimately required brain surgery by specialists at OHSU in Portland.
OHSU doctors and scientists working to address the opioid epidemic which has claimed thousands of lives and resulted in a doubling of the number of people who reported heroin addiction in a single decade, from 2003 to 2013.
Research published online in the journal Endocrinology found that a small synthetic molecule initially developed to lower cholesterol may slow or stop the devastating progression of the neurodegenerative disease adrenoleukodystrophy, or ALD. The study was conducted in a mouse model, but planning is under way for a human clinical trial.
Stroke medication currently available must be given within three hours to have the maximum benefit, but many patients do not make it to the hospital in time to receive it. A newly developed potential treatment involving the use of stem cells to promote brain recovery may greatly extend this window.
A unique OHSU psychiatric program supports immigrants and refugees, serving approximately 1,100 people in the Portland area, including 200 survivors of torture from countries including Iraq, Iran, Somalia, Ethiopia, Bosnia and Syria.
A powerful class of antibiotics provides life-saving relief for people with cystic fibrosis; however, a new study for the first time reveals the levels at which high cumulative dosages over time significantly increases the risk of permanent hearing loss in these patients.
U.S. taxpayers spent more than $650 million in 2013 and 2014 on one medication with questionable usefulness prescribed by less than 1 percent of clinicians, according to new research by scientists with OHSU and the OHSU/Oregon State University School of Pharmacy in Portland.
OHSU scientists have uncovered a method for quickly and efficiently mapping the genome of single cells within the body. Their findings, published Jan. 30 in the journal Nature Methods, clears the way for a significant advance in precision medicine, including cancer and many other disease areas.
A new discovery may unlock the answer to a vexing scientific question: How to conduct mitochondrial replacement therapy, a new gene-therapy technique, in such a way that safely prevents the transmission of harmful mitochondrial gene mutations from mothers to their children.
When the possibility of death is the only alternative, most people will opt for the most aggressive cancer treatments possible. The problem is, a new study by researchers at OHSU suggests that a robust combination of therapies that are effective in targeting the cancer can lead to harmful cognitive effects in the brain if the patient survives.
Families struggling with infertility or a genetic predisposition for debilitating mitochondrial diseases may someday benefit from a new breakthrough led by scientists at OHSU and the Salk Institute for Biological Studies.
A breakthrough study published online this week in the journal Nucleic Acids Research suggests that it may be possible to treat genetic disease detected in the womb by safely and efficiently delivering gene-altering therapies through a kind of reverse amniocentesis.
A panel of leading experts today issued the 4th Edition of the Guidelines for the Management of Severe Traumatic Brain Injury. The updated guidelines provide recommendations for 18 monitoring and treatment topics for patients with severe traumatic brain injuries, or TBI, including surgical procedures, the use of monitors that measure intracranial pressure, preventing and treating brain swelling, and nutrition.
New research reveals for the first time the atomic structures of a key molecular receptor in the brain, which opens the door for developing medications that could block activation of these receptors to address a variety of conditions, ranging from pain to high blood pressure to early formation of blood clots.
A first-of-its-kind controlled clinical trial found that a low-fat, plant-based diet significantly improved the health of people with multiple sclerosis by reducing both fatigue and weight. Those improvements go hand-in-hand with fighting some of the most debilitating effects of MS.